Prime Therapeutics — The October 2014 edition of Health Affairs is dedicated to Specialty Pharmaceutical Spending and Policy. It considers a host of issues related to specialty pharmaceuticals, from the promise they hold for curing or managing chronic diseases, to the risk they pose for exacerbating health care costs and the challenges they present to policy makers striving to balance both. Prime’s article in this issue is titled “Specialty Drug Coupons Lower Out-Of-Pocket Costs and May Improve Adherence At The Risk Of Increasing Premiums.” It examines insurers’ role in maintaining the affordability and accessibility of specialty drugs while maximizing their value.